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There are several matches for 'glutathione reductase'.
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8179 matches
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organism
protein
1)
Homo sapiens
GSR -
Glutathione
reductase
, mitochondrial; Maintains high levels of reduced
glutathione
in the cytosol.
[a.k.a. ENST00000318637, 1GRF, NM_001195104.2,
glutathione reductase
]
2)
Mus musculus
Gsr -
Glutathione
reductase
, mitochondrial; Maintains high levels of reduced
glutathione
in the cytosol.
[a.k.a. Gr1, CCDS22235.1, Gr-1,
Glutathione reductase
]
3)
Escherichia coli K12
gor - Glutathione oxidoreductase; Maintains high levels of reduced glutathione in the cytosol; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
[a.k.a. b3500, AAC76525.1, glutathione oxidoreductase,
Glutathione reductase
]
4)
Saccharomyces cerevisiae
GLR1 - Cytosolic and mitochondrial glutathione oxidoreductase; converts oxidized glutathione to reduced glutathione; cytosolic Glr1p is the main determinant of the glutathione redox state of the mitochondrial intermembrane space; mitochondrial Glr1p has a role in resistance to hyperoxia; protein abundance increases in response to DNA replication stress.
[a.k.a. YPL091W, NM_001183905, UPI000012BC08,
Glutathione reductase
]
5)
Homo sapiens
GSTO1 -
Glutathione
S-transferase omega-1; Exhibits
glutathione
-dependent thiol transferase and dehydroascorbate
reductase
activities. Has S-(phenacyl)
glutathione
reductase
activity. Has also
glutathione
S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.
[a.k.a. R-HSA-196854, Glutathione S-transferase omega 1, 1.8.5.1]
6)
Homo sapiens
TXNRD3 - Thioredoxin
reductase
3; Displays thioredoxin
reductase
, glutaredoxin and
glutathione
reductase
activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components (By similarity).
[a.k.a. ENSG00000197763, BC050032, ENSP00000430031]
7)
Homo sapiens
GLRX - Glutaredoxin-1; Has a
glutathione
-disulfide oxidoreductase activity in the presence of NADPH and
glutathione
reductase
. Reduces low molecular weight disulfides and proteins; Belongs to the glutaredoxin family.
[a.k.a. ENSP00000310075, NP_001230588, AAC35798.1]
8)
Homo sapiens
GLRX2 - Glutaredoxin-2, mitochondrial;
Glutathione
-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein
glutathione
-mixed disulfides. Can receive electrons not only from
glutathione
(GSH), but also from thioredoxin
reductase
supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylat [...]
[a.k.a. 2HT9, Glutaredoxin 2, 2CQ9]
9)
Homo sapiens
GSTO2 -
Glutathione
S-transferase omega-2; Exhibits
glutathione
-dependent thiol transferase activity. Has high dehydroascorbate
reductase
activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA). Belongs to the GST superfamily. Omega family.
[a.k.a. UPI000004D293, R-HSA-196854, uc001kyb.4]
10)
Homo sapiens
AKR1B10 - Aldo-keto
reductase
family 1 member B10; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays strong enzymatic activity toward all-trans- retinal, 9-cis-retinal, and 13-cis-retinal. Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4- hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their
glutathione
-conjugates carbonyls (GS-carbonyls). Displays no
reductase
activity towards glucose.
[a.k.a. R-HSA-388396, HSI, R-HSA-196854]
11)
Homo sapiens
CBR1 - Carbonyl
reductase
[NADPH] 1; NADPH-dependent
reductase
with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind
glutathione
, which explains its higher affinity for
glutathione
-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione.
[a.k.a. ENST00000530908, CH471079, SDR21C1]
12)
Mus musculus
Gsto1 -
Glutathione
S-transferase omega-1; Exhibits
glutathione
-dependent thiol transferase and dehydroascorbate
reductase
activities. Has S-(phenacyl)
glutathione
reductase
activity. Has also
glutathione
S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family.
[a.k.a. Glutathione S-transferase omega 1, mmu:14873, AAH85165.1]
13)
Mus musculus
Txnrd3 - Thioredoxin
reductase
3; Displays thioredoxin
reductase
, glutaredoxin and
glutathione
reductase
activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
[a.k.a. Q99MD6, Thioredoxin reductase 3, NM_001178059]
14)
Mus musculus
Glrx - Glutaredoxin-1; Has a
glutathione
-disulfide oxidoreductase activity in the presence of NADPH and
glutathione
reductase
. Reduces low molecular weight disulfides and proteins; Belongs to the glutaredoxin family.
[a.k.a. Q3U6L3, NM_001360151.1, CH466563]
15)
Mus musculus
Glrx2 - Glutaredoxin-2, mitochondrial;
Glutathione
-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein
glutathione
-mixed disulfides. Can receive electrons not only from
glutathione
(GSH), but also from thioredoxin
reductase
supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylat [...]
[a.k.a. ENSMUST00000050491, ENSMUSP00000121010, ENSMUSG00000018196]
16)
Mus musculus
Gsto2 -
Glutathione
S-transferase omega-2; Exhibits
glutathione
-dependent thiol transferase activity. Has high dehydroascorbate
reductase
activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA). Belongs to the GST superfamily. Omega family.
[a.k.a. UPI000019524D, ENSMUST00000237514, XP_030106923.1]
17)
Mus musculus
Cbr1 - Carbonyl
reductase
[NADPH] 1; NADPH-dependent
reductase
with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind
glutathione
, which explains its higher affinity for
glutathione
-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity) [...]
[a.k.a. NM_007620.2, Cbr, P48758]
18)
Drosophila melanogaster
Trxr-1 - Thioredoxin
reductase
1, mitochondrial; Thioredoxin system is a major player in
glutathione
metabolism, due to the demonstrated absence of a
glutathione
reductase
. Functionally interacts with the Sod/Cat reactive oxidation species (ROS) defense system and thereby has a role in preadult development and life span. Lack of a
glutathione
reductase
suggests antioxidant defense in Drosophila, and probably in related insects, differs fundamentally from that in other organisms; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
[a.k.a. FBgn0020653, Trxr-1-PB, Trxr-1-PC]
19)
Drosophila melanogaster
Trxr-2 - Thioredoxin
reductase
2, mitochondrial; Thioredoxin system is a major player in
glutathione
metabolism, due to the demonstrated absence of a
glutathione
reductase
. Functionally interacts with the Sod/Cat reactive oxidation species (ROS) defense system and thereby has a role in preadult development and life span. Lack of a
glutathione
reductase
suggests antioxidant defense in Drosophila, and probably in related insects, differs fundamentally from that in other organisms; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
[a.k.a. FBgn0037170, Trxr-2-PA, Q9VNT5]
20)
Drosophila melanogaster
Grx1t - Glutaredoxin 1, testis-specific; Electron transfer activity; protein disulfide oxidoreductase activity;
glutathione
-disulfide
reductase
activity. It is involved in the biological process described with: cellular response to oxidative stress; cell redox homeostasis.
[a.k.a. FBgn0034658, Grx1t-PA, dme:Dmel_CG7975]
8179 matches
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